Microarray analysis examines gene expression differences between diseased and healthy tissues by labeling and hybridizing cDNA on a chip. Emission levels are measured to determine gene activity, and public tools like GEO NCBI enable comparison of patient and control data. Statistically significant changes reveal potential therapeutic targets and disease mechanisms.
This blog introduces the concept of protein modeling, explaining its critical role in understanding protein structures and their biological functions. I have provided a detailed overview of three key protein modeling methods--Homology Modeling, Ab Initio Modeling and Threading. With practical examples, it shows how computational tools can solve complex biological problems.